Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
Phenotype | Diabetes.cls#NGT_versus_DMT
Upregulated in class | DMT
GeneSet | NKCELLSPATHWAY
Enrichment Score (ES) | -0.488252
Normalized Enrichment Score (NES) | -1.4722296
Nominal p-value | 0.063097514
FDR q-value | 1.0
FWER p-Value | 0.973
Table: GSEA Results Summary

Fig 1: Enrichment plot: NKCELLSPATHWAY
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
1 | KLRC4 | KLRC4 Entrez, Source | killer cell lectin-like receptor subfamily C, member 4 | 2516 | 0.946 | -0.1147 | No
2 | KLRC3 | KLRC3 Entrez, Source | killer cell lectin-like receptor subfamily C, member 3 | 3626 | 0.676 | -0.1449 | No
3 | B2M | B2M Entrez, Source | beta-2-microglobulin | 3723 | 0.654 | -0.1006 | No
4 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 6683 | 0.085 | -0.3163 | No
5 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 6797 | 0.064 | -0.3198 | No
6 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 7400 | -0.050 | -0.3611 | No
7 | PTPN6 | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 7951 | -0.162 | -0.3897 | No
8 | KLRD1 | KLRD1 Entrez, Source | killer cell lectin-like receptor subfamily D, member 1 | 8727 | -0.312 | -0.4234 | No
9 | HLA-A | HLA-A Entrez, Source | major histocompatibility complex, class I, A | 8875 | -0.345 | -0.4073 | No
10 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 9953 | -0.585 | -0.4422 | Yes
11 | VAV1 | VAV1 Entrez, Source | vav 1 oncogene | 9958 | -0.586 | -0.3964 | Yes
12 | SYK | SYK Entrez, Source | spleen tyrosine kinase | 10054 | -0.608 | -0.3557 | Yes
13 | LAT | LAT Entrez, Source | linker for activation of T cells | 10380 | -0.686 | -0.3261 | Yes
14 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11447 | -1.020 | -0.3259 | Yes
15 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 11781 | -1.155 | -0.2601 | Yes
16 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 11928 | -1.218 | -0.1752 | Yes
17 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 12644 | -1.629 | -0.1007 | Yes
18 | PTK2B | PTK2B Entrez, Source | PTK2B protein tyrosine kinase 2 beta | 12974 | -1.924 | 0.0260 | Yes
Table: GSEA details [plain text format]

Fig 2: NKCELLSPATHWAY
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: NKCELLSPATHWAY: Random ES distribution
Gene set null distribution of ES for NKCELLSPATHWAY