Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
Phenotype | Diabetes.cls#NGT_versus_DMT
Upregulated in class | NGT
GeneSet | P53_DOWN
Enrichment Score (ES) | 0.6811451
Normalized Enrichment Score (NES) | 1.8575836
Nominal p-value | 0.001980198
FDR q-value | 0.16306946
FWER p-Value | 0.186
Table: GSEA Results Summary

Fig 1: Enrichment plot: P53_DOWN
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
1 | ARL4A | ARL4A Entrez, Source | ADP-ribosylation factor-like 4A | 247 | 2.121 | 0.1186 | Yes
2 | INA | INA Entrez, Source | internexin neuronal intermediate filament protein, alpha | 343 | 1.979 | 0.2394 | Yes
3 | CDC6 | CDC6 Entrez, Source | CDC6 cell division cycle 6 homolog (S. cerevisiae) | 834 | 1.592 | 0.3055 | Yes
4 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 871 | 1.570 | 0.4042 | Yes
5 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 919 | 1.538 | 0.5002 | Yes
6 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 993 | 1.499 | 0.5916 | Yes
7 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 1141 | 1.434 | 0.6733 | Yes
8 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 1988 | 1.105 | 0.6811 | Yes
9 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 4365 | 0.526 | 0.5366 | No
10 | FOSL2 | FOSL2 Entrez, Source | FOS-like antigen 2 | 6045 | 0.202 | 0.4235 | No
11 | CPM | CPM Entrez, Source | carboxypeptidase M | 6294 | 0.157 | 0.4150 | No
12 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 6499 | 0.120 | 0.4074 | No
13 | PURA | PURA Entrez, Source | purine-rich element binding protein A | 7024 | 0.021 | 0.3694 | No
14 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 10363 | -0.682 | 0.1626 | No
15 | APBA2 | APBA2 Entrez, Source | amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like) | 11169 | -0.921 | 0.1617 | No
Table: GSEA details [plain text format]

Fig 2: P53_DOWN
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: P53_DOWN: Random ES distribution
Gene set null distribution of ES for P53_DOWN