Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
Phenotype | Diabetes.cls#NGT_versus_DMT
Upregulated in class | DMT
GeneSet | PITX2PATHWAY
Enrichment Score (ES) | -0.5558175
Normalized Enrichment Score (NES) | -1.4590697
Nominal p-value | 0.08982036
FDR q-value | 0.99743736
FWER p-Value | 0.976
Table: GSEA Results Summary

Fig 1: Enrichment plot: PITX2PATHWAY
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
1 | HDAC1 | HDAC1 Entrez, Source | histone deacetylase 1 | 1021 | 1.487 | 0.0127 | No
2 | WNT1 | WNT1 Entrez, Source | wingless-type MMTV integration site family, member 1 | 2674 | 0.902 | -0.0571 | No
3 | FZD1 | FZD1 Entrez, Source | frizzled homolog 1 (Drosophila) | 2711 | 0.893 | -0.0062 | No
4 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 4899 | 0.414 | -0.1456 | No
5 | PPARBP | PPARBP Entrez, Source | PPAR binding protein | 7225 | -0.015 | -0.3194 | No
6 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 7477 | -0.065 | -0.3344 | No
7 | LDB1 | LDB1 Entrez, Source | LIM domain binding 1 | 9197 | -0.415 | -0.4386 | No
8 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 10012 | -0.597 | -0.4639 | No
9 | AXIN1 | AXIN1 Entrez, Source | axin 1 | 11236 | -0.943 | -0.4991 | Yes
10 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 11957 | -1.229 | -0.4793 | Yes
11 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 12139 | -1.311 | -0.4140 | Yes
12 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 12295 | -1.403 | -0.3412 | Yes
13 | TRRAP | TRRAP Entrez, Source | transformation/transcription domain-associated protein | 12387 | -1.453 | -0.2606 | Yes
14 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 12434 | -1.485 | -0.1748 | Yes
15 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12582 | -1.579 | -0.0908 | Yes
16 | APC | APC Entrez, Source | adenomatosis polyposis coli | 13227 | -2.430 | 0.0070 | Yes
Table: GSEA details [plain text format]

Fig 2: PITX2PATHWAY
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: PITX2PATHWAY: Random ES distribution
Gene set null distribution of ES for PITX2PATHWAY